别 名Human Immunoglobulin A; hu IgA;
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human
产品应用ELISA=1:2000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 状Lyophilized powder
免 疫 原Native Human IgA: full length
亚 型IgG
纯化方法Affinity purified by Protein A
保存条件Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B-cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.
Subcellular Location:
Secreted.
SWISS:
P01876
Gene ID:
3493