英文名称

Cyclooxygenase 2 Rabbit pAb

中文名称

环氧合酶2/前列腺素内过氧化物合成酶2抗体

英文别名

PTGS2; COX 2; COX-2; Cyclooxygenase; Cyclooxygenase2; Cyclooxygenase-2; COX2; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PGHS2; PHS 2; PHS II; PHS2 ; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; TIS10II; PGH2_HUMAN.

产品应用

WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, Flow-Cyt=1μg/Test, IF=1:100-500, ELISA=1:5000-10000

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

交叉反应

Human, Mouse, Rat (predicted: Rabbit, Pig, Sheep, Cow, Dog)

抗体来源

Rabbit

免疫原

KLH conjugated synthetic peptide derived from human Cyclooxygenase 2: 501-604/604

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Polyclonal

理论分子量

65 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

亚基

Homodimer.

亚细胞定位

Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Post-translational modifications : S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.

翻译后修饰

S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.

相似性

Belongs to the prostaglandin G/H synthase family. Contains 1 EGF-like domain.

SWISS

P35354

Gene ID

5743

功能

Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.