Target Protein Information

Target Protein: ATF4
Concentration: 1 mg/ml
Form: Liquid
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG

Applications:

• WB (1:500-2000)

• IHC-P (1:100-500)

• IHC-F (1:100-500)

• Flow-Cyt (0.2 μg/test)

• ICC/IF (1:100)

• IF (1:100-500)

• ELISA (1:5000-10000)

Reactivity:

• Human

• Mouse

• Rat

• (Predicted: Rabbit, Pig, Sheep, Cow, Dog, Horse)

Predicted MW: 38 kDa
Entrez Gene: 468
Swiss Prot: P18848

Source:
KLH conjugated synthetic peptide derived from human ATF4: 251-351/351

Purification:
Affinity purified by Protein A

Storage:

• 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300, and 50% Glycerol

• Shipped at 4℃

• Store at -20℃ for one year

• Avoid repeated freeze/thaw cycles

Background:
ATF4 is a transcription factor originally identified as a widely expressed mammalian DNA binding protein capable of binding a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs), and CREB-like proteins. These transcription factors share a leucine zipper region involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).